ORAL HIV-ASSOCIATED KAPOSI SARCOMA: A COMPARISON BETWEEN IMMUNOHISTOCHEMISTRY AND qPCR TECHNIQUES FOR DETECTION OF HHV8
نویسندگان
چکیده
منابع مشابه
Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8).
The genome of the Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) was mapped with cosmid and phage genomic libraries from the BC-1 cell line. Its nucleotide sequence was determined except for a 3-kb region at the right end of the genome that was refractory to cloning. The BC-1 KSHV genome consists of a 140.5-kb-long unique coding region flanked by multiple G + C-rich 801-bp terminal repeat...
متن کاملDifferences in the frequency and function of HHV8-specific CD8 T cells between asymptomatic HHV8 infection and Kaposi sarcoma.
It is unclear how the immune response controls human herpesvirus 8 (HHV8; also known as Kaposi sarcoma-associated herpesvirus [KSHV]) replication and thereby prevents Kaposi sarcoma (KS). We compared CD8 T-cell responses to HHV8 latent (K12) and lytic (glycoprotein B, ORF6, ORF61, and ORF65) antigens in patients who spontaneously controlled the infection and in patients with posttransplantation...
متن کاملCyclin D1 expression and HHV8 in Kaposi sarcoma.
BACKGROUND Human herpesvirus 8 (HHV8) appears to be the agent responsible for Kaposi sarcoma. The mechanism remains undetermined but may involve cell cycle regulating genes including D type cyclins which are pivotal in cell cycle progression. Recent HHV8 genetic analysis has revealed the presence of a v-cyclin which is homologous to D type cyclins. AIMS First, to assess whether there is an in...
متن کاملAIDS: Acquired Immune Deficiency Syndrome HAART: Highly Active Antiretroviral Therapy HHV8: Human Herpes Virus 8 HIV: Human Immunodeficiency Virus HIV-KS: HIV associated Kaposi Sarcoma KS: Kaposi Sarcoma KSHV: Kaposi Sarcoma Herpes Virus
cAse rePOrts case no 1 A 33-year-old female of African descent was referred to the Oral Medicine Clinic from a neighbouring rural clinic. The patient presented with painful nodular lesions on her gingivae and hard palate, having noticed the enlarging lesions two months earlier when they started to impair her speech and mastication. She reported that she had been diagnosed with HiV infection two...
متن کاملOral HIV-Associated Kaposi Sarcoma: A Clinical Study from the Ga-Rankuwa Area, South Africa
UNLABELLED Background. Kaposi sarcoma (KS) is one of the most common neoplasms diagnosed in HIV-seropositive subjects. Oral involvement is frequent and is associated with a poor prognosis. The aim of this study was to characterize the features of oral HIV-KS in patients from Ga-Rankuwa, South Africa. Methods. All cases with confirmed oral HIV-KS treated at the oral medicine clinic in Ga-Rankuwa...
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ژورنال
عنوان ژورنال: Clinical and Laboratorial Research in Dentistry
سال: 2015
ISSN: 2357-8041
DOI: 10.11606/issn.2357-8041.clrd.2015.97224